Push both ways to avoid a jam

Ways To Avoid Obviousness - Type Double Patenting

Law360, New York (May 13, 2016, 12:15 PM ET) -Obviousness-type double patenting (ODP) is a judicially created doctrine intended to prevent an improper timewise extension of patent rights by prohibiting the issuance to a single entity of claims in a second patent which are not "patentably distinct" from the claims of a first patent.[1] Claims are not patentably distinct from each other if one cl...

IFT-A goes both ways

Protrusion provides a prognosis H ow a cancer cell migrates across a 2D surface says little about its ability to move through a 3D matrix, Meyer et al. reveal, but measuring membrane protrusion can be much more informative. A metastasizing tumor cell moves through 3D tissues, yet, largely because they're easier to perform, most studies of cell migration are carried out on 2D surfaces. Meyer et ...

Artifacts in trimethylsilyl derivatization reactions and ways to avoid them.

Trimethylsilyl derivatives are routinely employed in gas chromatography to increase the volatility and stability of organic compounds containing active hydrogens. Normally only the desired derivative is formed when organic compounds are derivatized with common silylation reagents. However, some compounds form additional unexpected derivatives or by-products (artifacts). Artifact formation leads...

Barcan Both Ways

A GTPase that goes both ways

Survival gets more complicated NTF and related proteins have been shown to promote the survival of motoneurons in two different settings: during embryonic development and after nerve injury in adults. Because the signal and the response are apparently the same in the two situations, a simple explanation is that embryonic and adult neurons use the same signaling pathways to promote survival. But...